1. In a large pot or Dutch oven, cook the ground beef over medium heat until browned. Drain any excess grease.

2. Add chopped onion, celery, and bell pepper. Cook until softened, about 5 minutes.

3. Stir in tomato sauce, diced tomatoes, tomatoes with green chilies, kidney beans, and pinto beans.

4. Add chili powder, cumin, garlic powder, salt, and pepper. Pour in water and stir to combine.

5. Bring to a low boil, then reduce heat and simmer uncovered for at least 1 hour, stirring occasionally.

6. Taste and adjust seasoning before serving. Add cayenne or hot sauce for more heat if desired.