This creamy Cajun chicken linguine is what comfort food dreams are made of. Juicy, pan-seared chicken breasts are coated in bold Cajun spices and served over silky linguine tossed in a rich garlic mozzarella sauce. It’s the kind of dish that feels fancy enough for date night but easy enough for a weeknight dinner.

What makes this pasta dish shine is the balance between spice and cream. The Cajun seasoning gives the chicken that irresistible smoky heat, while the mozzarella garlic sauce mellows everything out with its velvety texture and cheesy richness. If you’re craving bold flavor and ultra-creamy pasta in one forkful, you’re going to love every bite of this.

Why You’ll Love This Creamy Cajun Chicken Linguine

This recipe delivers restaurant-quality results in under an hour. The chicken is incredibly tender, thanks to the quick sear-and-simmer method. The mozzarella garlic sauce clings to every strand of linguine, transforming it into a decadent bite each time. Plus, it’s easy to tweak—add mushrooms, spinach, or even shrimp for variety.

It’s also perfect for leftovers, and the flavors deepen beautifully overnight. Whether you’re cooking for family or meal-prepping for the week, this dish is a standout.

What Kind of Linguine or Pasta Works Best for Creamy Cajun Chicken?

Linguine is the ideal base for this recipe because it strikes that perfect balance between thinness and chew. It holds up to the rich sauce without becoming too heavy. But don’t feel boxed in—fettuccine, spaghetti, or even penne work well here too.

If you’re looking to lighten things up a bit, try using whole wheat or chickpea pasta. Just be mindful of cook times and taste, as the sauce will cling differently depending on the pasta base. Whatever you choose, make sure to cook it al dente so it can finish absorbing flavor when tossed with the sauce.

Ingredients for the Creamy Cajun Chicken Linguine

To bring out the bold Cajun flavor while keeping everything rich and balanced, each ingredient here plays a crucial role. You don’t need anything complicated—just high-impact ingredients that deliver big on taste.

Linguine
Boneless skinless chicken breasts
Cajun seasoning
Olive oil
Butter
Garlic cloves
All-purpose flour
Whole milk
Heavy cream
Mozzarella cheese
Parmesan cheese
Salt and pepper
Fresh parsley

Creamy Cajun Chicken Linguine with Garlic Mozzarella Sauce 2

How To Make the Creamy Cajun Chicken Linguine

Step 1: Season and Sear the Chicken

Pat the chicken dry and generously coat both sides with Cajun seasoning. Heat olive oil in a large skillet and sear the chicken on medium-high heat until golden brown on both sides and cooked through. Remove from the pan and let it rest.

Step 2: Cook the Linguine

While the chicken is cooking, bring a pot of salted water to a boil and cook the linguine until just al dente. Drain and set aside, reserving a bit of the pasta water.

Step 3: Make the Garlic Mozzarella Sauce

In the same skillet used for the chicken, melt butter over medium heat and sauté minced garlic until fragrant. Stir in flour to create a roux, cooking for 1-2 minutes. Slowly whisk in milk and heavy cream, letting it simmer until thickened. Stir in mozzarella and Parmesan until melted and smooth.

Step 4: Slice Chicken and Combine

Slice the rested chicken into strips. Add the cooked linguine to the sauce, using reserved pasta water if needed to loosen it. Stir until well coated.

Step 5: Serve and Garnish

Top the creamy pasta with sliced Cajun chicken. Sprinkle fresh parsley and extra Parmesan on top before serving. Serve hot and enjoy the creamy, spicy, and cheesy goodness in every bite.

How to Serve and Store Creamy Cajun Chicken Linguine

This recipe serves 4 people generously, especially when paired with a fresh side or bread. It’s perfect for a cozy dinner or to impress friends with something indulgent and flavorful. When serving, make sure the pasta is well coated with the sauce, and don’t be shy with the extra Parmesan or parsley on top.

If you have leftovers, they store well in an airtight container in the refrigerator for up to 3 days. Reheat on the stove over low heat or in the microwave in 30-second intervals, adding a splash of milk or cream to keep the sauce silky. Avoid freezing, as the creamy sauce may separate.

What to Serve With Creamy Cajun Chicken Linguine?

Garlic Bread

A warm, crusty slice of garlic bread is perfect for soaking up any extra sauce left on your plate.

Roasted Asparagus

The char and slight bitterness of roasted asparagus balances beautifully with the creamy pasta.

Caesar Salad

A crisp Caesar salad adds a refreshing bite and cuts through the richness of the dish.

Sautéed Mushrooms

Earthy and savory mushrooms make a great veggie companion to the Cajun spice and creamy sauce.

Lemon Green Beans

Green beans with a splash of lemon bring brightness that complements the spice.

Herby Chicken Meatball Bowl (as a side or mini dish)

If you want to lean into protein-packed sides, a small portion of this works surprisingly well alongside pasta.

Classic Caprese Salad

Tomatoes and fresh mozzarella with basil and balsamic drizzle offer a cool contrast.

Creamy Tomato Spinach Pasta (for a pasta pairing)

It sounds bold, but a small spoon of another creamy pasta like this on the side can be a fun twist for a dinner spread.

Want More Pasta Ideas with a Kick?

If you loved this Creamy Cajun Chicken Linguine, you’ll want to dive into these bold and comforting dishes next:

Try the indulgent One Pot Creamy Sausage Rigatoni for a simple yet savory flavor explosion.
Explore a lighter take with Creamy Tomato Spinach Pasta that still satisfies your craving for sauce.
Switch proteins with the spicy twist in Creamy Cajun Shrimp Pasta for a seafood spin.
Love chicken but want a different sauce? The Tuscan Chicken Pasta might become your next go-to.
Need a cozy skillet option? Check out the Garlic Butter Chicken Balls with Creamy Parmesan Pasta.

Save This Recipe For Later

📌 Save this recipe to your Pinterest dinner board so you can revisit it any time.

And tell me in the comments how yours turned out! Did you add mushrooms or extra chili flakes? Maybe swap the mozzarella for gouda? I love hearing how you tweak recipes to make them your own.

Explore beautifully curated pasta dishes and comfort classics on Janet Dishes on Pinterest and find your new favorite flavor combination.

Conclusion

Creamy Cajun Chicken Linguine with Garlic Mozzarella Sauce is one of those dishes that brings bold flavor, satisfying texture, and cozy comfort all in one. Whether you make it as a quick weeknight treat or a special weekend meal, it’s sure to impress with minimal fuss. Rich, spicy, and ultra-satisfying—this one deserves a regular spot in your dinner rotation.