There’s something about a creamy, spicy pasta that just speaks to comfort food cravings on another level. This dish is a full-on flavor explosion with the heat of Cajun-seasoned beef, silky Velveeta cheese sauce, and tender rotini pasta that holds every bit of that delicious richness. The melted mozzarella adds the perfect stringy, gooey finish that takes this meal from simple to sensational.

Whether you’re feeding a hungry family or planning a weeknight dinner that feels like a splurge, this Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce delivers every time. It’s hearty, quick to make, and will easily become one of your most-loved pasta recipes. Pair it with a crisp salad or serve it solo—either way, it’s an instant crowd-pleaser.

Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce 2

Why You’ll Love This Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce

This recipe packs the bold, satisfying flavors of Southern comfort into a single skillet. The Cajun spices give the beef a punch of personality, while Velveeta melts seamlessly into a rich sauce that clings to each swirl of rotini. Mozzarella brings that ooey-gooey finish everyone loves in a baked pasta. It’s a perfect fusion of spice, creaminess, and cheesy goodness.

What Kind of Pasta Should I Use?

Rotini is ideal for this dish because its corkscrew shape holds onto the sauce better than smoother noodles. However, if you don’t have rotini on hand, penne or fusilli can work just as well. You want something with grooves and curves that can trap all the creamy Cajun cheese goodness in every bite.

Ingredients for the Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce

To create this dish, you’ll need a mix of spicy, cheesy, and creamy elements to bring all the flavors together. Each ingredient serves a purpose in building a rich, hearty pasta that’s comforting and unforgettable.

Rotini pasta: Its spiral shape holds the sauce beautifully, making every bite flavorful.
Ground beef: Provides a meaty base that absorbs all the Cajun seasoning.
Cajun seasoning: Brings the bold, spicy kick to the beef.
Velveeta cheese: Melts into a silky smooth sauce with a creamy texture.
Mozzarella cheese: Adds stretchy, gooey richness, especially when melted on top.
Heavy cream: Enhances the creamy texture of the sauce.
Garlic powder: Gives depth to the overall flavor without overpowering.
Onion powder: Adds a subtle sweetness and rounds out the spices.
Salt and pepper: To balance and season the dish to taste.

How To Make the Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce

Step 1: Boil the Pasta

Bring a large pot of salted water to a boil and cook the rotini until al dente. Drain and set aside.

Step 2: Cook the Beef

In a large skillet over medium heat, add the ground beef. Cook until browned, breaking it up as it cooks. Drain excess fat, then season the meat with Cajun seasoning, garlic powder, onion powder, salt, and pepper.

Step 3: Make the Cheese Sauce

Reduce heat to low. Add cubed Velveeta cheese and heavy cream into the skillet with the beef. Stir until the cheese melts completely and the sauce becomes creamy.

Step 4: Combine Pasta and Sauce

Add the cooked rotini into the skillet and toss well so the pasta is fully coated in the sauce.

Step 5: Add Mozzarella and Finish

Sprinkle mozzarella over the top. Cover the skillet with a lid for a few minutes to allow the mozzarella to melt. Once gooey and stretchy, serve hot.

How to Serve and Store Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce

This creamy rotini dish is best served hot and fresh right out of the skillet. The cheese is perfectly melty, and the sauce clings beautifully to the pasta. It feeds about 4 to 6 people, depending on portion size. If you’re serving it for a cozy family dinner, consider pairing it with a green salad and some crusty bread to round things out.

To store leftovers, transfer the cooled pasta into an airtight container and refrigerate for up to 3 days. To reheat, add a splash of milk or cream when warming it on the stove or in the microwave to loosen the sauce and bring back its creamy consistency.

What to Serve With Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce?

Garlic Bread

A golden, buttery slice of garlic bread is perfect for soaking up any leftover sauce on your plate.

Caesar Salad

Crisp romaine lettuce with a creamy dressing adds a fresh, cooling contrast to the heat of the Cajun beef.

Roasted Broccoli

Oven-roasted broccoli adds a bit of crunch and earthiness to balance the creamy richness.

Grilled Asparagus

Slightly charred asparagus spears offer a light and flavorful pairing.

Classic Caprese Salad

Tomatoes, mozzarella, and basil bring a refreshing counterbalance and continue the cheesy theme.

Creamed Spinach

Silky, garlicky spinach is a rich and cozy side that blends right in with the pasta.

Spicy Pickled Veggies

Add a little crunch and a tangy bite to complement the creamy base of the dish.

Simple Cucumber Salad

Cool, crisp cucumbers dressed lightly with vinegar and dill refresh the palate between bites.

Want More Pasta Ideas with a Cheesy Twist?

If you love the bold creaminess of this rotini dish, you’ll probably fall hard for these other flavor-packed pasta favorites:

Creamy Tomato Spinach Pasta brings a veggie-forward version with tangy tomato depth.
Delicious Ooey Gooey Mac and Cheese is a childhood favorite grown up with melty cheese magic.
One Pot Creamy Sausage Rigatoni is savory, hearty, and perfectly comforting on busy weeknights.
Creamy Cajun Sausage Pasta adds smoky spice and flavor bombs in every bite.
Creamy Cottage Cheese Pasta Sauce lightens up your creamy craving with a high-protein punch.

Save This Recipe For Later

📌 Save this recipe to your Pinterest dinner board so you can come back to it anytime.

And let me know in the comments how yours turned out. Did you go extra spicy or keep it mild? Did you toss in bell peppers or top it with jalapeños?

I love seeing how you personalize these recipes to fit your family’s taste. Don’t hesitate to drop questions below—we’re all learning together!

Explore beautifully curated comfort meals and cheesy pasta favorites on Janet Dishes on Pinterest and discover your next go-to dinner.