Comfort food doesn’t get much better than this stuffed Italian meatloaf. It’s everything you love about a hearty meatloaf but elevated with layers of gooey mozzarella cheese, Italian herbs, and a rich tomato glaze that caramelizes beautifully in the oven. This is the kind of dish that fills your kitchen with incredible aromas and your table with happy faces.

Unlike the dry meatloaf memories of the past, this version stays moist and flavorful thanks to the melted cheese tucked inside and the perfect blend of seasonings. It’s a satisfying main course that pairs beautifully with pasta, roasted veggies, or even crusty bread. And the leftovers? Even better the next day.

Why You’ll Love This Stuffed Italian Meatloaf

This meatloaf is a cozy classic with an Italian twist. The inside is filled with stretchy mozzarella and herbs that infuse every bite. It’s easy enough for a weeknight dinner but impressive enough for guests. You get the nostalgic feeling of a home-cooked favorite, with a flavorful upgrade that makes it unforgettable.

What Kind of Ground Meat Should I Use?

While traditional meatloaf recipes often use a mix of beef and pork, you can stick to ground beef for a classic richness or mix it with Italian sausage for extra spice and flavor. Just be sure to use meat with a bit of fat (around 80/20) to keep it juicy during baking.

Ingredients for the Stuffed Italian Meatloaf

Choosing the right ingredients makes all the difference in flavor and texture. Each component adds something special, from moisture and structure to bold taste.

Ground beef
Breadcrumbs
Parmesan cheese
Eggs
Garlic
Italian seasoning
Mozzarella cheese
Fresh parsley
Salt and pepper
Tomato sauce

How To Make the Stuffed Italian Meatloaf

Step 1: Mix the Meatloaf Base

In a large bowl, combine the ground beef, breadcrumbs, grated Parmesan, eggs, minced garlic, Italian seasoning, chopped parsley, salt, and pepper. Mix gently with your hands until just combined.

Step 2: Flatten and Stuff

On a piece of parchment paper or foil, press the meat mixture into a large rectangle. Lay the mozzarella cheese slices or shreds down the center of the meat, leaving space on the edges.

Step 3: Roll and Seal

Carefully roll the meatloaf, jelly-roll style, using the parchment paper to guide you. Pinch the seams and edges closed to keep the cheese tucked inside.

Step 4: Bake It Up

Place the rolled meatloaf seam-side down on a greased baking sheet or in a loaf pan. Spoon tomato sauce over the top and bake at 375°F (190°C) for 45 to 55 minutes, or until the meat is cooked through and the cheese is bubbling.

Step 5: Rest and Slice

Let the meatloaf rest for 10 minutes before slicing. This helps everything set and makes slicing easier.

How to Serve and Store This Meatloaf

This stuffed Italian meatloaf feeds 6 to 8 people generously, making it ideal for family dinners or small gatherings. Serve it warm with extra sauce on top. Store leftovers in an airtight container in the refrigerator for up to 4 days, or freeze slices for up to 3 months. Reheat in the oven or microwave with a splash of sauce to keep it moist.

What to Serve With Stuffed Italian Meatloaf?

Garlic Mashed Potatoes

Creamy mashed potatoes with garlic and butter are a perfect match for the bold flavors of this meatloaf.

Roasted Brussels Sprouts

Their crispy texture and caramelized edges balance out the richness of the dish.

Creamy Polenta

Smooth, buttery polenta offers a rustic Italian side that’s pure comfort.

Classic Caesar Salad

The crisp lettuce and tangy dressing provide a refreshing contrast to the hearty meat.

Pasta with Olive Oil and Herbs

Keep it simple with pasta tossed in olive oil, garlic, and fresh herbs.

Sauteed Green Beans

A light and easy side that adds color and freshness.

Crusty Italian Bread

For mopping up all the saucy goodness on your plate.

Want More Comfort Food Ideas?

If you love this hearty Italian-style main course, try some of these cozy favorites next:

French Onion Ground Beef and Rice Casserole for savory one-dish comfort.
Creamy Smothered Chicken with Spinach, Potatoes and Mushrooms when you’re craving creamy and filling.
Creamy Tomato Spinach Pasta for a vegetarian twist with rich tomato flavor.
Ultimate Cheesy Ground Beef Melt if you’re after melty, meaty indulgence.
Zucchini Lasagna when you want a lighter take without sacrificing Italian flavor.

Save This Recipe For Later

📌 Save this recipe to your Pinterest dinner board so you can come back to it any time.

Let me know in the comments if you gave it a spicy twist or added extra cheese. I love hearing how you make these recipes your own. And feel free to ask questions if you need help getting that perfect slice.

Explore beautifully curated health-boosting drinks and cozy dinner ideas on Janet Dishes on Pinterest and discover your new go-to for comfort food with flavor.